Module 4
Assessments
Assessments in Module 4 include one open response item and one formative assessment.
Open Response Item
You have been infected by a virus. Describe the two possible sequences of events your body would undertake to destroy the virus.
Cell-mediated response
- Macrophages engulf a virus and display antigens on its surface
- Helper T cells recognize these antigens and are stimulated to produce interleukin 1
- Interleukin 1 causes helper T cells to divide and produce interleukin-2
- Interleukin-2 stimulates killer T cells to divide
- Killer T cells attack infected cells and destroy them
- Macrophages clean up the mess
Humoral Response
- Virus antigen binds to receptors on the surface of a B cell
- This causes the secretion of antibodies specific to these antigens
- Interleukin 2 stimulates B cells to divide and differentiate into memory B cells and more anti-producing B cells
- Antibodies bind to viruses and viral infected cells
- Macrophages clean up the mess
Formative assessment
Students select a disease on the Timeline of Infectious Diseases. Then, ask them to prepare a diagram, drawing, animation, cartoon or other means of displaying how the immune system mobilizes to ward off infection for their chosen pathogen.